A Postdoctoral Associate position is available in the LaVoie Lab inthe Center for Translational Research in Neurodegenerative Diseaseat the McKnight Brain Institute. The overall goal of the LaVoie Labis to elucidate the earliest molecular events responsible for adultonset neurodegenerative diseases. The lab approaches thesedevastating disorders from both the perspective that specificinherited gene mutations linked to familial forms can providevaluable insight, as well as maintaining a focus on aspects of thefar more common sporadic forms. The research is funded and directedby Professor Matthew LaVoie in the Department of Neurology and thelab employs a diverse array of state-of-the-art tools to accomplishthese goals including a series of novel knockin animal models,iPSC-based neuronal and glial cultures, and CRISPR/Cas9 genomeediting.The LaVoie Lab is located in a vibrant neuroscience researchatmosphere that includes the Center for Translational Research inNeurodegenerative Disease, the Biomedical Sciences Center, theCenter for Neurogenetics, the McKnight Brain Institute and theFixel Institute for Neurologic Disorders. The successful applicantwill join dedicated, experienced and highly motivated researchersand collaborators. The research is fast-paced and exciting, thelaboratories are modern and well-equipped, and there are superbopportunities for advanced training in relevant techniques.A recent PhD, MD or MD/PhD, and experience in a field directlyrelevant to neurodegenerative diseases. Applicants should haveexcellent oral and written communication skills, and experience inthe collection and analysis of data. Preferred candidates will havea strong record of productivity from previous training experiences.They must have a high level of independence in the design andexecution of in vitro and in vivo experiments.Salary will be commensurate with experience andqualifications.The successful applicant would join a team studying familialParkinson’s disease centered on pathogenic mutations in the Parkinand LRRK2 genes. Parkin is a ubiquitin E3 ligase which is highlyexpressed in neurons. Autosomal recessive, loss-of-functionmutations in the Parkin gene are associated with an often earlyonset form of Parkinson’s disease. The appointment represents asuperb training opportunity to learn/apply skills in cell culture,iPSC maintenance and differentiation, and primary cell culture workfrom novel mouse models. High content image analysis, along with adiverse array of biochemical assays will be used routinely.Applications should include a CV, cover letter of intent, and alist of 3 references with contact information. Review ofapplications will begin immediately and will continue untilposition is filled. Questions may be directed to Dr. Matthew LaVoieat [email protected]; however, applications must be submitted online.All candidates for employment are subject to a pre-employmentscreening which includes a review of criminal records, referencechecks, and verification of education.The selected candidate will be required to provide an officialtranscript to the hiring department upon hire. A transcript willnot be considered “official” if a designation of “Issued toStudent” is visible. Degrees earned from an educational institutionoutside of the United States require evaluation by a professionalcredentialing service provider approved by the National Associationof Credential Evaluation Services (NACES), which can be found at http://www.naces.org/ .The University of Florida is an equal opportunity institutiondedicated to building a broadly diverse and inclusive faculty andstaff. Searches are conducted in accordance with Florida’s SunshineLaw. If an accommodation due to disability is needed in order toapply for this position, please call (352) 392-2477 or the FloridaRelay System at (800) 955-8771 (TDD).#category=35The University of Florida is committed to non-discrimination withrespect to race, creed, color, religion, age, disability, sex,sexual orientation, gender identity and expression, marital status,national origin, political opinions or affiliations, geneticinformation and veteran status in all aspects of employmentincluding recruitment, hiring, promotions, transfers, discipline,terminations, wage and salary administration, benefits, andtraining.